Final Project Overview

Jackson Gazin, Ashley Mullan, Anh Nguyen

Problem Statement

Among those who take cholesterol lowering medication, does taking this cholesterol lowering medication change their systolic blood pressure?

Background

  • Controlling blood pressure (BP) reduces the risk for cardiovascular disease.
  • Ways to control blood pressure include exercise, the white coat effect, pharmacotherapy, a healthy diet, regulating sodium, reducing alcohol use, smoking, getting sleep, reducing stress, and regular health check-ups.
  • ANH PUT ANY OTHER LIT STUFF HERE

DAG

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Statistical Analysis

  • Clean the dataset
  • Build a propensity model and ATT weights
  • Run diagnostics on the propensity model
  • Build an outcome model
  • Run sensitivity analysis

Key Results

  • The cleaned data had 20,822 rows and 3 columns after deriving \(X, Y, \boldsymbol{Z}\) from our adjustment set and dropping missing values.
  • The propensity model and ATT weighting produced data that was balanced.
  • Using a sandwich estimator to derive the standard errors, we observe an ATT of 9.26 with 95% CI (8.578,9.941).
  • A conservative unmeasured confounding variable setup would require an effect size of over 6 times the ATT to tip the CI to the null at the 95% level.

Diagnostic Plots

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Diagnostic Plots

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Diagnostic Plots

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notes: we assume missing at random X is cholesterol med use, Z is total cholesterol, Y is mean blood pressure up next: diagnostic plots :::

Conclusion

JACKSON PLEASE PUT CONCLUSION HERE